{"id":4326,"date":"2020-05-14T14:11:23","date_gmt":"2020-05-14T12:11:23","guid":{"rendered":"http:\/\/us-patente.com.www243.your-server.de\/?page_id=4326"},"modified":"2022-09-14T12:24:28","modified_gmt":"2022-09-14T10:24:28","slug":"scientific-publications","status":"publish","type":"page","link":"https:\/\/us-patente.com\/en\/attorneys\/dr-siegfried-j-w-ruppert\/scientific-publications\/","title":{"rendered":"Scientific Publications"},"content":{"rendered":"<div class=\"container-fluid\"><div class=\"container\"><div id=\"element_1177609942947\" class=\"el_row row\"><div class=\"inner-row\"><div id=\"element_2\" class=\"el_column col-md-12\"><div class=\"inner-column\"><div id=\"element-3\" class=\"section-head left layout-petro\"><div><h2 class=\"section-main-title\">Dipl.-Biol. Siegfried J.W. Ruppert<\/h2><\/div><\/div><div id=\"element_4177609942980\" class=\"el_text\"><h4>U.S. Attorney | U.S. Patent Attorney<\/h4><\/div><div id=\"element_5177609942950\" class=\"el_text\"><h3 style=\"color: #c7b29a;\">Scientific Publications<\/h3>\n<p>During his scientific career Dr. Ruppert was involved in the research projects described in the publications listed below:<\/p>\n<ul>\n<li>Shao, Z., Siegert, J.L., <strong>Ruppert, S<\/strong>. and Robbins, P.D. (1997). Rb interacts with TAFII250\/TFIID through multiple domains distinct from E2F and viral oncoprotein binding regions.\u00a0 <a href=\"https:\/\/www.nature.com\/articles\/1201204\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Oncogene<\/em> <u>15<\/u>, 385-392. <\/a><\/li>\n<li>Marsters, S.A., Pitti, R.M., Donahue, C.J., <strong>Ruppert, S<\/strong>., Roberts, P., Bauer, K.D. and Ashkenazi, A. (1996). Activation of apoptosis by Apo-2 ligand is independent of FADD but blocked by CrmA.\u00a0 <a href=\"https:\/\/www.cell.com\/current-biology\/fulltext\/S0960-9822(09)00456-4?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0960982209004564%3Fshowall%3Dtrue\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Current Biology <\/em><u>6<\/u>, 750-752.<\/a><\/li>\n<li>Pitti, R.M., Marsters, S.A., <strong>Ruppert, S<\/strong>., Donahue, C.J., Moore, A. and Ashkenazi, A. (1996). Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. <a href=\"https:\/\/www.jbc.org\/content\/271\/22\/12687.long\" target=\"_blank\" rel=\"noopener noreferrer\"><em>J. Biol. Chem. <\/em><u>271<\/u>, 12687-12690.<\/a><\/li>\n<li>Dikstein, R., <strong>Ruppert, S<\/strong>. and Tjian, R. (1996). TAFII250 is a bipartite protein kinase that phosphorylates the basal transcription factor RAP74.\u00a0 <a href=\"https:\/\/www.cell.com\/cell\/fulltext\/S0092-8674(00)81055-7?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867400810557%3Fshowall%3Dtrue\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Cell<\/em> <u>84<\/u>, 781-790.<\/a><\/li>\n<li><strong>Ruppert, S<\/strong>. and Tjian, R. (1995). Human TAFII250 interacts with RAP74: implications for RNA polymerase II initiation.\u00a0<a href=\"http:\/\/genesdev.cshlp.org\/content\/9\/22\/2747.long\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Genes &amp; Dev.<\/em> <u>9<\/u>, 2747-2755.<\/a><\/li>\n<li>Shao, Z., <strong>Ruppert, S<\/strong>. and Robbins, P.D. (1995). The retinoblastoma-susceptibility gene product binds directly to the human TATA-binding protein-associated factor TAFII250.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC42115\/\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Proc. Natl. Acad. Sci. USA<\/em> <u>92<\/u>, 3115-3119. <\/a><\/li>\n<li>Tansey, W.P., <strong>Ruppert, S<\/strong>., Tjian, R. and Herr, W. (1994). Multiple regions of TBP participate in the response to transcriptional activators in vivo.\u00a0<a href=\"http:\/\/genesdev.cshlp.org\/content\/8\/22\/2756.long\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Genes &amp; Dev.<\/em> <u>8<\/u>, 2756-2769.<\/a><\/li>\n<li>Kelsey, G., <strong>Ruppert, S<\/strong>., Beermann, F., Grund, C., Tanguay, R.M. and Sch\u00fctz, G. (1993). Rescue of mice homozygous for lethal albino deletions: Implications for an animal model for human liver disease tyrosinaemia type 1.\u00a0<a href=\"http:\/\/genesdev.cshlp.org\/content\/7\/12a\/2285.long\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Genes &amp; Dev<\/em>. <u>7 (12a)<\/u>, 2285-2297.<\/a><\/li>\n<li>Shelly, L.L., Lei, K.-J., Pan, C.-J., Sakata, S.F., <strong>Ruppert, S<\/strong>., Sch\u00fctz, G. and Chou, J.Y. (1993). Isolation of the gene for murine glucose-6-phosphatase, the enzyme deficient in glycogen storage disease Type 1A.\u00a0\u00a0<a href=\"https:\/\/www.jbc.org\/content\/268\/29\/21482.long\" target=\"_blank\" rel=\"noopener noreferrer\"><em>J. Biol. Chem.<\/em> <u>268<\/u>, 21482-21485.<\/a><\/li>\n<li>Weinzierl, R.O.J., <strong>Ruppert, S<\/strong>., Dynlacht, B.D., Tanese, N. and Tjian, R. (1993). Cloning and expression of <em>Drosophila<\/em> TAFII60 and human TAFII70 reveals conserved interactions with other subunits of TFIID.\u00a0<a href=\"https:\/\/www.embopress.org\/doi\/abs\/10.1002\/j.1460-2075.1993.tb06226.x?sid=nlm%3Apubmed\" target=\"_blank\" rel=\"noopener noreferrer\"><em>EMBO Journal <\/em><u>12 (13)<\/u>, 5303-5309.<\/a><\/li>\n<li><strong>Ruppert, S<\/strong>., Wang, E.H. and Tjian, R. (1993). Cloning and expression of human TAFII250: a TBP-associated factor implicated in cell-cycle regulation.\u00a0<a href=\"https:\/\/www.nature.com\/articles\/362175a0\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Nature<\/em> <u>362<\/u>, 175-179.<\/a><\/li>\n<li>Sakata, S.F., Shelly, L.L. <strong>Ruppert, S<\/strong>., Sch\u00fctz, G. and Chou, J.Y. (1993). Cloning and expression of murine S-adenosylmethionine synthetase.\u00a0<a href=\"https:\/\/www.jbc.org\/content\/268\/19\/13978.long\" target=\"_blank\" rel=\"noopener noreferrer\"><em>J. Biol. Chem.<\/em> <u>268<\/u>, 13978-13986.<\/a><\/li>\n<li>Beermann, F., Schedl, A., <strong>Ruppert, S<\/strong>., Ganss, R., Schmid, E., Klueppel, M., Hummler, E. and Sch\u00fctz, G. (1993). The mouse tyrosinase gene: Pigment cell-specific gene expression in transgenic mice. In: Pharmacology of the Skin, Vol. 5, <a href=\"https:\/\/www.karger.com\/BookSeries\/Home\/224129\" target=\"_blank\" rel=\"noopener noreferrer\"><em>From Molecular Biology to Therapeutics<\/em>, B.A. Bernhard and B. Shroot (eds), Karger, Basel, 57-62.<\/a><\/li>\n<li>Kelsey, G., <strong>Ruppert, S<\/strong>., Schedl, A., Schmid, E., Thies, E. and Sch\u00fctz, G. (1992). Multiple effects on liver-specific gene expression in albino lethal mice caused by deficiency of an enzyme in tyrosine metabolism.\u00a0<a href=\"https:\/\/journals.biologists.com\/jcs\/article\/1992\/Supplement_16\/117\/57843\/Multiple-effects-on-liver-specific-gene-expression\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Journal of Cell Science &#8211; Supplement<\/em> <u>16<\/u>, 117-122.<\/a><\/li>\n<li>Rosewicz, S., Vogt, D., Harth, N., Grund, C., Franke, W.W., <strong>Ruppert, S<\/strong>., Schweitzer, E., Riecken, E.O. and Wiedenmann, B. (1992). An amphicrine pancreatic cell line: AR42J cells combine exocrine and neuroendocrine properties.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/1361433\" target=\"_blank\" rel=\"noopener noreferrer\"><em>European Journal of Cell Biology<\/em> <u>59<\/u>, 80-91.<\/a><\/li>\n<li>Beermann, F., Schmid, E., Ganss, R., Sch\u00fctz, G. and <strong>Ruppert, S<\/strong>. (1992). Molecular characterization of the mouse tyrosinase gene: Pigment cell-specific expression in transgenic mice.\u00a0<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/j.1600-0749.1992.tb00552.x\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Pigment Cell Research<\/em> <u>5<\/u>, 295-9.<\/a><\/li>\n<li><strong>Ruppert, S<\/strong>., Kelsey, G., Schedl, A., Schmid, E., Thies, E. and Sch\u00fctz, G. (1992). Deficiency of an enzyme of tyrosine metabolism underlies altered gene expression in newborn liver of lethal albino mice.\u00a0 <a href=\"http:\/\/genesdev.cshlp.org\/content\/6\/8\/1430.long\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Genes &amp; Dev. <\/em><u>6<\/u>, 1430-1443.<\/a><\/li>\n<li>Schedl, A., <strong>Ruppert, S<\/strong>., Kelsey, G., Thies, E., Niswander, L., Magnuson, T., Klebig, M.L., Rinchik, E.M. and Sch\u00fctz, G. (1992). Chromosome jumping from flanking markers defines the minimal region for alf\/hsdr-1 within the albino-deletion complex. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0888754305802186?via%3Dihub\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Genomics <\/em><u>14<\/u>, 288-297.<\/a><\/li>\n<li>Kelsey, G., Schedl, A., <strong>Ruppert, S<\/strong>., Klebig, M.L., Niswander, L., Magnuson, T., Rinchik, E.M. and Sch\u00fctz, G. (1992). Physical mapping of the albino-deletion complex in the mouse to localize <em>alf\/hsdr-1<\/em>, a locus required for neonatal survival. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0888754305802174?via%3Dihub\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Genomics<\/em> <u>14<\/u>, 275-287.<\/a><\/li>\n<li>Cole, T., Copeland, N.G., Gilbert, D.J., Jenkins, N.A., Sch\u00fctz, G. and <strong>Ruppert, S<\/strong>. (1992). The mouse CREB (cAMP responsive element binding protein) gene: structure, promoter analysis, and chromosomal localization.\u00a0<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/088875439290010P?via%3Dihub\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Genomics<\/em> <u>13 (4)<\/u>, 974-982.<\/a><\/li>\n<li><strong>Ruppert, S<\/strong>., Cole, T.J., Boshart, M., Schmid, E. and Sch\u00fctz, G. (1992). Multiple mRNA isoforms of the transcription activator protein CREB: generation by alternative splicing and specific expression in spermatocytes.\u00a0<a href=\"https:\/\/www.embopress.org\/doi\/abs\/10.1002\/j.1460-2075.1992.tb05195.x?sid=nlm%3Apubmed\" target=\"_blank\" rel=\"noopener noreferrer\"><em>EMBO Journal<\/em> <u>11<\/u>, 1503-1512.<\/a><\/li>\n<li>Sharan, S.K., Holdener-Kenny, B., <strong>Ruppert, S<\/strong>., Schedl, A., Kelsey, G., Rinchik, E.M. and Magnuson, T.\u00a0 (1991). The albino-deletion complex of the mouse: molecular mapping of deletion breakpoints that define regions necessary for development of the embryonic and extraembryonic ectoderm.\u00a0<a href=\"https:\/\/www.genetics.org\/content\/129\/3\/825.long\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Genetics <\/em><u>129<\/u>, 825-832.<\/a><\/li>\n<li>Beermann, F.,<strong> Ruppert, S<\/strong>., Hummler, E. and Sch\u00fctz, G. (1991). Tyrosinase as a marker for transgenic mice.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC333741\/\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Nucleic Acids Res<\/em>. <u>19<\/u>, 958.<\/a><\/li>\n<li>Kl\u00fcppel, M., Beermann, F., <strong>Ruppert, S<\/strong>., Schmid, E., Hummler, E. and Sch\u00fctz, G. (1991). The mouse tyrosinase promoter is sufficient for expression in melanocytes and in the pigmented epithelium of the retina.\u00a0<a href=\"https:\/\/www.pnas.org\/content\/88\/9\/3777.long\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Proc. Natl. Acad. Sci. USA<\/em> <u>88<\/u>, 3777-3781.<\/a><\/li>\n<li>Chou, J.Y., <strong>Ruppert, S<\/strong>., Shelly, L.L. and Pan, C.-J. (1991). Isolation and characterization of mouse hepatocyte lines carrying a lethal albino deletion.\u00a0<a href=\"https:\/\/www.jbc.org\/content\/266\/9\/5716.long\" target=\"_blank\" rel=\"noopener noreferrer\"><em>J. Biol. Chem.<\/em> <u>266<\/u>, 5716-5722.<\/a><\/li>\n<li>Niswander, L., Kelsey, G., Schedl, A., <strong>Ruppert, S<\/strong>., Sharan, S.K., Holdener-Kenny, B., Rinchik, E.M., Edstr\u00f6m, J.-E. &amp; Magnuson, T. (1991). Molecular mapping of albino deletions associated with early embryonic lethality in the mouse.\u00a0<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/0888754391902346?via%3Dihub\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Genomics<\/em> <u>9<\/u>, 162-169.<\/a><\/li>\n<li>Nitsch, D., <strong>Ruppert, S<\/strong>., Kelsey, G., Schedl, A., Weih, F., Stewart, F., Str\u00e4hle, U., Schmid, W., deVack, C., Reik, A., Boshart, M. and Sch\u00fctz, G. (1991). Hormonal and liver-specific control of expression of the tyrosine aminotransferase gene. In: <a href=\"https:\/\/epub.ub.uni-muenchen.de\/3223\/1\/3223.pdf\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Molecular Aspects of Cellular Regulation.<\/em><\/a> Vol. 6 The Hormonal Control Regulation of Gene Transcription. p 223-234. P. Cohen and J.G. Foulkes (eds). Elsevier Science. Publishers B.V. Amsterdam, The Netherlands.<\/li>\n<li>Beermann, F., <strong>Ruppert, S<\/strong>., Hummler, E., Bosch, F.X., M\u00fcller, G., R\u00fcther, U. and Sch\u00fctz, G. (1990). Rescue of the albino phenotype by introduction of a functional tyrosinase gene into mice.\u00a0<a href=\"https:\/\/www.embopress.org\/doi\/abs\/10.1002\/j.1460-2075.1990.tb07470.x?sid=nlm%3Apubmed\" target=\"_blank\" rel=\"noopener noreferrer\"><em>EMBO Journal<\/em><u>9<\/u>, 2819-2826.<\/a><\/li>\n<li>Sch\u00f6ler, H.R., <strong>Ruppert, S<\/strong>., Suzuki, N., Chowdhury, K. and Gruss, P. (1990). New type of POU domain in germ line-specific protein Oct-4.\u00a0<a href=\"https:\/\/www.nature.com\/articles\/344435a0\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Nature<\/em> <u>344<\/u>, 435-439.<\/a><\/li>\n<li><strong>Ruppert, S<\/strong>., Boshart, M., Bosch, F.X., Schmid, W., Fournier, K. and Sch\u00fctz. G. (1990). Two genetically defined <em>trans<\/em>-acting loci coordinately regulate overlapping sets of liver-specific genes.\u00a0 <a href=\"https:\/\/www.cell.com\/cell\/pdf\/0092-8674(90)90200-X.pdf?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2F009286749090200X%3Fshowall%3Dtrue\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Cell<\/em> <u>61<\/u>, 895-904.<\/a><\/li>\n<li>Ryseck, R.-P., Macdonald-Bravo, H., Matt\u00e9i, M.-G., <strong>Ruppert, S<\/strong>. and Bravo, R. (1989). Structure, mapping and expression of a growth factor inducible gene encoding a putative nuclear hormonal binding receptor.\u00a0<a href=\"https:\/\/www.embopress.org\/doi\/abs\/10.1002\/j.1460-2075.1989.tb08494.x?sid=nlm%3Apubmed\" target=\"_blank\" rel=\"noopener noreferrer\"><em>EMBO Journal<\/em> <u>11<\/u>, 3327-3335.<\/a><\/li>\n<li>Kelsey, G.D., <strong>Ruppert, S<\/strong>., Boshart, M., Schedl, A., Schmid, W. and Sch\u00fctz, G. (1989). The albino perinatal lethal deletion: Identification of affected mRNAs and mapping of the locus by pulsed-field gel electrophoresis.\u00a0 NATO ASI Series, Vol. H34. Vectors as Tools for the Study of Normal and Abnormal Growth and Differentiation. <a href=\"https:\/\/link.springer.com\/chapter\/10.1007\/978-3-642-74197-5_5\">pp 47-62.<\/a><\/li>\n<li>M\u00fcller, M.M., <strong>Ruppert, S<\/strong>., Schaffner, W. and Matthias, P. (1988). A cloned octamer transcription factor stimulates transcription from lymphoid-specific promoters in non-B cells.\u00a0 <a href=\"https:\/\/www.nature.com\/articles\/336544a0\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Nature<\/em> <u>336<\/u>, 544-551.<\/a><\/li>\n<li>M\u00fcller, G., <strong>Ruppert, S<\/strong>., Schmid, E. and Sch\u00fctz, G. (1988). Functional analysis of alternatively spliced tyrosinase gene transcripts.\u00a0<a href=\"https:\/\/www.embopress.org\/doi\/abs\/10.1002\/j.1460-2075.1988.tb03126.x?sid=nlm%3Apubmed\" target=\"_blank\" rel=\"noopener noreferrer\"><em>EMBO Journal<\/em> <u>9<\/u>, 2723-2730.<\/a><\/li>\n<li><strong>Ruppert, S<\/strong>., M\u00fcller, G., Kwon, B. and Sch\u00fctz, G. (1988). Multiple transcripts of the mouse tyrosinase gene are generated by alternative splicing.\u00a0<a href=\"https:\/\/www.embopress.org\/doi\/abs\/10.1002\/j.1460-2075.1988.tb03125.x?sid=nlm%3Apubmed\" target=\"_blank\" rel=\"noopener noreferrer\"><em>EMBO Journal<\/em><u>9<\/u>, 2715-2722.<\/a><\/li>\n<li>Becker, P.B., <strong>Ruppert, S<\/strong>. and Sch\u00fctz, G. (1987). Genomic footprinting reveals cell type-specific DNA binding of ubiquitous factors.\u00a0<a href=\"https:\/\/www.cell.com\/cell\/pdf\/0092-8674(87)90639-8.pdf?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2F0092867487906398%3Fshowall%3Dtrue\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Cell<\/em> <u>51<\/u>, 435-443.<\/a><\/li>\n<li>M\u00fcller, G., Scherer, G., Zentgraf, H., <strong>Ruppert, S<\/strong>., Herrmann, B., Lehrach, H. and Sch\u00fctz, G. (1985). Isolation, characterization and chromosomal mapping of the mouse tyrosine aminotransferase gene.\u00a0<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/0022283685902876?via%3Dihub\" target=\"_blank\" rel=\"noopener noreferrer\"><em>J. Mol. Biol.<\/em> <u>184<\/u>, 367-373.<\/a><\/li>\n<li><strong>Ruppert, S<\/strong>., Scherer, G. and Sch\u00fctz, G. (1984). Recent gene conversion involving bovine vasopressin and oxytocin precursor genes suggested by nucleotide sequence.\u00a0<a href=\"https:\/\/www.nature.com\/articles\/308554a0\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Nature<\/em> <u>308<\/u>, 554-557.<\/a><\/li>\n<li><a name=\"uspatente\"><\/a>Land H., Grez, M., <strong>Ruppert, S<\/strong>., Schmale, H., Rehbein, M., Richter, D. and Sch\u00fctz, G. (1983). Deduced amino acid sequence from the bovine oxytocin-neurophysin I precursor cDNA.\u00a0<a href=\"https:\/\/www.nature.com\/articles\/302342a0\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Nature<\/em> <u>302<\/u>, 342-344.<\/a><\/li>\n<\/ul>\n<p>As a scientist at the renowned University of California at Berkeley and at Genentech, Inc., the first biotech company in the U.S., Dr. Ruppert also gained his first experience with U.S. patents.\u00a0 Here, his scientific work, among others, led to <a href=\"http:\/\/us-patente.com.www243.your-server.de\/en\/anwalte\/dr-siegfried-j-w-ruppert\/scientific-publications\/\">three U.S. patents<\/a>.<\/p>\n<h3 style=\"color: #c7b29a;\">U.S. Patents<\/h3>\n<p>Dr. Ruppert&#8217;s scientific work at the University of California at Berkeley and at the U.S. biotech company Genentech, Inc. led, among other things, to the U.S. patents listed below:<\/p>\n<ul>\n<li><strong>Ruppert, S<\/strong>., (1999) United States Patent <a href=\"http:\/\/www.freepatentsonline.com\/5891637.html\" target=\"_blank\" rel=\"noopener noreferrer\">No. 5,891,637<\/a> \u201cConstruction of full-length cDNA libraries.\u201d<\/li>\n<li>Tjian, R., Comai, L., Dynlacht, B.D., Hoey, T., <strong>Ruppert, S<\/strong>., Tanese, N., Wang, E., Weinzierl, R.O.J. (1997) United States Patent <a href=\"http:\/\/www.freepatentsonline.com\/5637686.html\" target=\"_blank\" rel=\"noopener noreferrer\">No. 5,637,686<\/a> \u201cTATA-binding protein associated factors, nucleic acids.\u201d<\/li>\n<li>Tjian, R., Comai, L., Dynlacht, B.D., Hoey, T., <strong>Ruppert, S<\/strong>., Tanese, N., Wang, E., Weinzierl, R.O.J. (1996) United States Patent <a href=\"http:\/\/www.freepatentsonline.com\/5534410.html\" target=\"_blank\" rel=\"noopener noreferrer\">No. 5,534,410<\/a> \u201cTATA-binding protein associated factors drug screens.\u201d<\/li>\n<\/ul><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":4283,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/us-patente.com\/en\/wp-json\/wp\/v2\/pages\/4326"}],"collection":[{"href":"https:\/\/us-patente.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/us-patente.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/us-patente.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/us-patente.com\/en\/wp-json\/wp\/v2\/comments?post=4326"}],"version-history":[{"count":13,"href":"https:\/\/us-patente.com\/en\/wp-json\/wp\/v2\/pages\/4326\/revisions"}],"predecessor-version":[{"id":4883,"href":"https:\/\/us-patente.com\/en\/wp-json\/wp\/v2\/pages\/4326\/revisions\/4883"}],"up":[{"embeddable":true,"href":"https:\/\/us-patente.com\/en\/wp-json\/wp\/v2\/pages\/4283"}],"wp:attachment":[{"href":"https:\/\/us-patente.com\/en\/wp-json\/wp\/v2\/media?parent=4326"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}